Website maintenance is planned from 8:00 a.m. CDT Saturday, July 27, through 9:00 p.m. CDT Sunday, July 28. Brief disruptions may occur during this time.
Repeat testing using the nucleic acid amplification test (within seven days) for C. difficile is not recommended when the symptoms represent a single episode of diarrheal illness. Studies have shown that repeat testing using the nucleic acid amplification test within a seven-day period yields only a 2% diagnostic yield. Exceptions should only be made in the setting of an institutional epidemic or when C. difficile infection is highly suspected with no alternative diagnosis, but for which the initial test is negative and symptoms persist or worsen.