MedicationMechanism of actionDosage
Magnesium sulfateIntracellular calcium antagonism4 to 6 g loading dose; then 2 to 4 g IV every hour
Terbutaline (Bricanyl)Beta2-adrenergic receptor agonist sympathomimetic; decreases free intracellular calcium ions0.25 to 0.5 mg SC every three to four hours
Ritodrine (Yutopar)Same as terbutaline0.05 to 0.35 mg per minute IV
Nifedipine (Procardia)Calcium channel blocker5 to 10 mg SL every 15 to 20 minutes (up to four times), then 10 to 20 mg orally every four to six hours
Indomethacin (Indocin)Prostaglandin inhibitor50- to 100-mg rectal suppository, then 25 to 50 mg orally every six hours