| Increase dopamine levels |
| Levodopa-carbidopa (Sinemet) | Precursor with enzyme inhibitor | Parkinson's disease | Dizziness, nausea, hallucinations and others | 25/100 mg three times daily | $ 70 |
| Amantadine (Symmetrel) | Dopamine reuptake inhibitor | Parkinsonism | Confusion, nausea, hallucination | 100 mg twice daily | 54.50 (20 to 26) |
| May lead to neuroleptic malignant syndrome |
| Stimulate dopamine receptors |
| Bromocriptine (Parlodel) | Dopamine agonist (receptor stimulation) | Parkinson's disease, others (?) | † | 1.25 mg twice daily | 29 |
| Pergolide (Permax) | Same as bromocriptine | Same as bromocriptine | † | 0.05 mg at bedtime | 23.50 |
| Pramipexole (Mirapex) | Same as bromocriptine | Same as bromocriptine | † | 0.125 mg three times daily | 65.50 |
| Ropinirole (Requip) | Same as bromocriptine | Same as bromocriptine | † | 0.25 mg three times daily | 84 |
| Inhibit dopamine metabolism |
| Selegiline (Eldepryl) | MAO-B inhibitor | Parkinson's disease, others (?) | Insomnia, headaches, sweating | 5 mg twice daily | 153.50 (122 to 138) |
| Contraindicated with concurrent use of MAO-A drugs |
| Tolcapone (Tasmar) | COMT inhibitor | Parkinson's disease | Dizziness, orthostasis, diarrhea | 100 mg three times daily | 167 |
| Liver function must be monitored |
| Other |
| Diphenhydramine (Benadryl) | Antihistamine | Acute dystonia, parkinsonism | Drowsiness, dry mouth, blurred vision | 25 mg at bedtime | 3 (1 to 2) |
| Trihexyphenidyl (Artane) | Anticholinergic activity | Tremor | Confusion, dry mouth, nausea | 0.5 to 1 mg twice daily | 6‡ |
| Benztropine (Cogentin) | Same as trihexyphenidyl | Same as trihexyphenidyl | Same as trihexyphenidyl | 1 to 2 mg twice daily | 13 (6.50 to 7) |