Major features
Pruritus
Chronic or relapsing dermatitis
Personal or family history of atopic disease
Typical distribution and morphology of atopic dermatitis rash:
Facial and extensor surfaces in infants and young children
Flexure lichenification in older children and adults
Minor features
Eyes
Cataracts (anterior subcapsular)
Keratoconus
Infraorbital folds affected
Facial pallor
Palmar hyperlinearity
Xerosis
Pityriasis alba
White dermatographism
Ichthyosis
Keratosis pilaris
Nonspecific dermatitis of the hands and feet
Nipple eczema
Positive type I hypersensitivity skin tests
Propensity for cutaneous infections
Elevated serum IgE level
Food intolerance
Impaired cell-mediated immunity
Erythroderma
Early age of onset