Major features |
Pruritus |
Chronic or relapsing dermatitis |
Personal or family history of atopic disease |
Typical distribution and morphology of atopic dermatitis rash: |
| Facial and extensor surfaces in infants and young children |
| Flexure lichenification in older children and adults |
Minor features |
Eyes |
| Cataracts (anterior subcapsular) |
| Keratoconus |
| Infraorbital folds affected |
Facial pallor |
Palmar hyperlinearity |
Xerosis |
Pityriasis alba |
White dermatographism |
Ichthyosis |
Keratosis pilaris |
Nonspecific dermatitis of the hands and feet |
Nipple eczema |
Positive type I hypersensitivity skin tests |
Propensity for cutaneous infections |
Elevated serum IgE level |
Food intolerance |
Impaired cell-mediated immunity |
Erythroderma |
Early age of onset |