| Constitutional symptoms | Fever, fatigue, malaise, anorexia, weight loss | Any type of vasculitis |
| Polymyalgia rheumatica | Proximal muscle pain with morning stiffness | Giant cell arteritis; less commonly, other vasculitides |
| Nondestructive oligoarthritis | Joint swelling, warmth, painful range of motion | Polyarteritis, Wegener's granulomatosis, Churg-Strauss vasculitis |
| Skin lesions | Livedo reticularis, necrotic lesions, ulcers, nodules, digital tip infarcts | Polyarteritis, Churg-Strauss vasculitis, Wegener's granulomatosis, hypersensitivity vasculitis |
| Palpable purpura | Any type of vasculitis except giant cell arteritis and Takayasu's arteritis |
| Multiple mononeuropathy (mononeuritis multiplex) | Injury to two or more separate peripheral nerves (e.g., patient presents with both right foot drop and left wrist drop) | Polyarteritis, Churg-Strauss vasculitis, Wegener's granulomatosis, cryoglobulinemia |
| Renal involvement | Ischemic renal failure related to arteritis | Polyarteritis, Takayasu's arteritis; less commonly, Churg-Strauss vasculitis and Wegener's granulomatosis |
| Glomerulonephritis | Microscopic polyangiitis, Wegener's granulomatosis, cryoglobulinemia, Churg-Strauss vasculitis, Henoch-Schönlein purpura |