Neuropathic pain | Antidepressants |
| | Amitriptyline (Elavil), 10 mg three times daily |
| | Imipramine (Tofranil), 10 mg three times daily |
| Anticonvulsants |
| | Carbamazepine (Tegretol), 200 mg twice daily |
| | Gabapentin (Neurontin), 100 mg per day* |
| | Divalproex (Depakote), 125 mg once or twice daily |
| | Phenytoin (Dilantin), 100 mg three times daily |
| Local anesthetics |
| | Mexiletine (Mexitil), 150 mg three times daily |
| Capsaicin (Zostrix) applied to affected area three times daily |
| Clonidine (Catapres), 0.1 mg per day |
| Baclofen (Lioresal), 5 mg three times daily, with the dosage increased every third day until symptoms resolve |
Inflammation | Corticosteroids |
| | Dexamethasone (Decadron), 16 mg per day in divided doses |
| | Methylprednisolone (Medrol), 120 mg per day in divided doses |
| Nonsteroidal medications (see Table 2) |
Anxiety | Benzodiazepines |
| | Lorazepam (Ativan), 0.5 mg three times daily |
| | Diazepam (Valium), 5 mg three times daily |
| Antihistamines |
| | Hydroxyzine (Atarax), 25 mg three times daily |
| | Diphenhydramine (Benadryl), 25 mg three times daily |
Bone metastasis | Pamidronate (Aredia), 90 mg once a month, administered in an infusion over 2 to 4 hours |
| Calcitonin (Calcimar), 100 IU per day administered subcutaneously or intramuscularly |
Muscle spasms | Baclofen, 5 mg three times daily, with the dosage increased every third day until symptoms resolve |
| Benzodiazepines |
| | Lorazepam, 0.5 mg three times daily |
| | Diazepam, 5 mg three times daily |
Generalized chronic pain | Antidepressants |
| | Amitriptyline, 10 mg three times daily |
| | Imipramine, 10 mg three times daily |
| Corticosteroids |
| | Dexamethasone, 16 mg per day in divided doses |
| | Methylprednisolone, 120 mg per day in divided doses |