Type of pain or associated conditionMedications and starting dosages
Neuropathic painAntidepressants
Amitriptyline (Elavil), 10 mg three times daily
Imipramine (Tofranil), 10 mg three times daily
Anticonvulsants
Carbamazepine (Tegretol), 200 mg twice daily
Gabapentin (Neurontin), 100 mg per day*
Divalproex (Depakote), 125 mg once or twice daily
Phenytoin (Dilantin), 100 mg three times daily
Local anesthetics
Mexiletine (Mexitil), 150 mg three times daily
Capsaicin (Zostrix) applied to affected area three times daily
Clonidine (Catapres), 0.1 mg per day
Baclofen (Lioresal), 5 mg three times daily, with the dosage increased every third day until symptoms resolve
InflammationCorticosteroids
Dexamethasone (Decadron), 16 mg per day in divided doses
Methylprednisolone (Medrol), 120 mg per day in divided doses
Nonsteroidal medications (see Table 2)
AnxietyBenzodiazepines
Lorazepam (Ativan), 0.5 mg three times daily
Diazepam (Valium), 5 mg three times daily
Antihistamines
Hydroxyzine (Atarax), 25 mg three times daily
Diphenhydramine (Benadryl), 25 mg three times daily
Bone metastasisPamidronate (Aredia), 90 mg once a month, administered in an infusion over 2 to 4 hours
Calcitonin (Calcimar), 100 IU per day administered subcutaneously or intramuscularly
Muscle spasmsBaclofen, 5 mg three times daily, with the dosage increased every third day until symptoms resolve
Benzodiazepines
Lorazepam, 0.5 mg three times daily
Diazepam, 5 mg three times daily
Generalized chronic painAntidepressants
Amitriptyline, 10 mg three times daily
Imipramine, 10 mg three times daily
Corticosteroids
Dexamethasone, 16 mg per day in divided doses
Methylprednisolone, 120 mg per day in divided doses