Drug		Usual dosage for adults*	Formulations	Cost per pill (generic)†
Acetic acids
Diclofenac potassium (Cataflam)		100 to 200 mg daily	50 mg	$1.81 (1.53)
Diclofenac sodium
	Immediate-release (Voltaren)	100 to 200 mg daily	25 mg	0.66 (0.44 to 0.47)
			50 mg	1.29 (0.86 to 1.06)
			75 mg	1.56 (1.06 to 1.28)
	Delayed-release (Voltaren XR)	100 to 200 mg daily	100 mg	3.12
	With misoprostol (Arthrotec)	50 mg three times daily 50 mg three or four times daily for rheumatoid arthritis	50 mg diclofenac sodium with 200 μg misoprostol 75 mg diclofenac sodium with 200 μg misoprostol	1.47
				1.54
Etodolac
	Immediate-release (Lodine)	600 to 1,000 mg daily given in two divided doses	200 mg	1.37 (1.11)
			300 mg	1.55 (1.25 to 1.26)
			400 mg	1.64 (1.26 to 1.40)
			500 mg	1.65 (1.46)
	Extended-release (Lodine XL)	400 to 1,000 mg daily	400 mg	1.50
			500 mg	1.57
			600 mg	2.85
Sulindac (Clinoril)		150 mg twice daily (maximum dosage: 400 mg daily)	150 mg	1.12 (0.90 to 1.15)
			200 mg	1.38 (0.75 to 0.91)
Propionic acids
Flurbiprofen (Ansaid)		200 to 300 mg daily given in two to four divided doses	50 mg	1.15 (0.60 to 0.72)
			100 mg	1.80 (1.08 to 1.23)
Ibuprofen (Motrin)		400 to 800 mg three or four times daily (maximum dosage: 3,200 mg daily)	200 mg	0.21 (0.10 to 0.13)
			400 mg	0.24 (0.08 to 0.20)
			600 mg	0.35 (0.04 to 0.21)
			800 mg	0.45 (0.06 to 0.38)
Ketoprofen
	Immediate-release (Orudis)	150 to 300 mg daily given in three to four divided doses	25 mg	0.96 (0.74)
			50 mg	1.17 (0.90 to 0.92)
			75 mg	1.30 (0.98 to 1.02)
	Extended-release (Orvail)	150 to 300 mg daily given in three or four divided doses	100 mg	2.19
			150 mg	2.67
			200 mg	3.01 (2.49)
	Over-the-counter (Orudis KT)	12.5 mg every 4 to 6 hours	12.5 mg	0.09
Naproxen
	Immediate-release (Naprosyn)	250 to 500 mg twice daily	250 mg	1.18 (0.12)
			375 mg	1.46 (0.21)
			500 mg	1.88 (0.18)
	Delayed-release (EC Naprosyn)	750 or 1,000 mg daily	375 mg	1.77
			500 mg	2.03
Naproxen sodium
	Immediate-release (Anaprox, Anaprox DS)	275 or 550 mg twice daily	275 mg	0.84 (0.67 to 0.74)
			550 mg	1.31 (1.04 to 1.15)
	Extended-release (Naprelan)	750 or 1,000 mg daily	375 mg	1.27
			500 mg	1.56
	Over-the-counter (Aleve)	220 mg every 8 to 12 hours	220 mg	0.14 (0.06 to 0.14)
Oxaprozin (Daypro)		1,200 mg daily	600 mg	1.53
Nonacidic agents
Nabumetone (Relafen)		1,000 to 2,000 mg given once daily or twice daily in divided doses	500 mg	1.21
			750 mg	1.43
Cyclooxygenase-2 inhibitors
Celecoxib (Celebrex)		100 mg twice daily or 200 mg daily for osteoarthritis 100 to 200 mg twice daily for rheumatoid arthritis	100 mg 200 mg	1.43
				2.42
				—
Rofecoxib (Vioxx)		12.5 to 25 mg daily for osteoarthritis	12.5 mg	2.42
			25 mg	2.42
		50 mg daily for primar dysmenorrhea and acute pain	50 mg	3.54
			12.5 or 25 mg in 5-mL suspension	3.60 for 12.5 or 25 mg per 5-mL suspension