| Age limit for use | 7 years and older | 18 years and older |
| Route of administration | Oral (inhalation) | Oral (capsule) |
| Dosage | 10 mg twice daily† | 75 mg twice daily |
| Precautions and warnings | Not generally recommended in patients with asthma, COPD or other underlying airway disease; may cause bronchospasm and allergic-like reactions | A dosage reduction is recommended for patients with a creatinine clearance of less than 30 mL per minute (0.50 mL per second). |
| Metabolism and elimination | Renally excreted as unchanged drug Not a substrate or inhibitor of cytochrome P450 isoenzymes | Converted to oseltamivir carboxylate primarily by hepatic esterases Not a substrate or inhibitor of cytochrome P450 isoenzymes |
| Side effects | Nasal and throat irritation, cough, headache; bronchospasm and decreased expiratory flow rate in patients with asthma or COPD | Nausea and vomiting, which may be reduced by administration with food |
| Drug interactions | Unlikely, but has not been studied completely | Unlikely, but has not been studied completely |
| Pregnancy category | C | C |
| Cost for five-day treatment course‡ | $44.40 | $53 |