| Beta-adrenergic blockers and diuretics |
| Atenolol-chlorthalidone | Tenoretic |
| Bisoprolol fumarate–hydrochlorothiazide | Ziac |
| Metoprolol tartrate–hydrochlorothiazide | Lopressor |
| HCT |
| Nadolol-bendroflumethiazide | Corzide |
| Propranolol hydrochloride (extended release)–hydrochlorothiazide | Inderide LA |
| Timolol maleate–hydrochlorothiazide | Timolide |
| ACE inhibitors and diuretics |
| Benazepril hydrochloride–hydrochlorothiazide | Lotensin HCT |
| Captopril-hydrochlorothiazide | Capozide |
| Enalapril maleate–hydrochlorothiazide | Vaseretic |
| Lisinopril-hydrochlorothiazide | Prinzide |
| Angiotensin II receptor antagonists and diuretics |
| Losartan potassium–hydrochlorothiazide | Hyzaar |
| Calcium antagonists and ACE inhibitors |
| Amlodipine besylate–benazepril hydrochloride | Lotrel |
| Diltiazem malate (extended release)–enalapril maleate | Teczem |
| Verapamil hydrochloride (extended release)–trandolapril | Tarka |
| Felodipine–enalapril maleate | Lexxel |
| Other combinations |
| Triamterene (37.5, 50 or 75 mg)–hydrochlorothiazide (25 or 50 mg) | Dyazide |
| Spironolactone (25 or 50 mg)–hydrochlorothiazide (25 or 50 mg) | Aldactazide |
| Amiloride hydrochloride (5 mg)–hydrochlorothiazide (50 mg) | Moduretic |
| Guanethidine monosulfate (10 mg)–hydrochlorothiazide (25 mg) | Esimil |
| Hydralazine hydrochloride (25, 50 or 100 mg)–hydrochlorothiazide (25 or 50 mg) | Apresazide |
| Methyldopa (250 or 500 mg)–hydrochlorothiazide (15, 25, 30 or 50 mg) | Aldoril |
| Reserpine (0.125 mg)–hydrochlorothiazide (25 or 50 mg) | Hydropres |
| Reserpine (0.01 mg)–hydralazine hydrochloride (25 mg)–hydrochlorothiazide (15 mg) | Ser-Ap-Es |
| Clonidine hydrochloride (0.1, 0.2 or 0.3 mg)–chlorthalidone (15 mg) | Combipres |
| Methyldopa (250 mg)–chlorothiazide (150 or 250 mg) | Aldoclor |
| Reserpine (0.125 or 0.25 mg)–chlorthalidone (25 or 50 mg) | Regroton |
| Reserpine (0.125 mg)–chlorothiazide (250 or 500 mg) | Diupres |
| Prazosin hydrochloride (1, 2 or 5 mg)–polythiazide (0.5 mg) | Minizide |