Risk category | Age < 60 years | Age ≥ 60 years | Women of childbearing age | |
---|---|---|---|---|
Low risk | No treatment* or low-dose aspirin‡ | Not applicable | No treatment† or low-dose aspirin‡ | |
Intermediate risk | No treatment* or anagrelide‡ or low-dose aspirin‡ | Not applicable | No treatment† or low-dose aspirin‡ | |
Platelet count <1,500 × 103 per μL (1,500 × 109 per L) | ||||
Intermediate risk | No treatment† or anagrelide‡ | Not applicable | No treatment† | |
Platelet count >1,500 × 103 per μL | ||||
High risk | Hydroxyurea§ or anagrelide* plus low-dose aspirin† | Hydroxyurea§ plus low-dose aspirin† | Interferon alfa|| plus low-dose aspirin† |