TSH levelFree T4 levelFree T3 levelLikely diagnosis
HighLowLowPrimary hypothyroidism
High (>10 μU per mL [10 mU per L])NormalNormalSubclinical hypothyroidism with high risk for future development of overt hypothyroidism
High (6 to 10 μU per mL [6 to 10 mU per L])NormalNormalSubclinical hypothyroidism with low risk for future development of overt hypothyroidism
HighHighLowCongenital absence of T4-T3–converting enzyme; amiodarone (Cordarone) effect on T4-T3 conversion
HighHighHighPeripheral thyroid hormone resistance
LowLowLowPituitary thyroid deficiency or recent withdrawal of thyroxine after excessive replacement therapy