High | Low | Low | Primary hypothyroidism |
High (>10 μU per mL [10 mU per L]) | Normal | Normal | Subclinical hypothyroidism with high risk for future development of overt hypothyroidism |
High (6 to 10 μU per mL [6 to 10 mU per L]) | Normal | Normal | Subclinical hypothyroidism with low risk for future development of overt hypothyroidism |
High | High | Low | Congenital absence of T4-T3–converting enzyme; amiodarone (Cordarone) effect on T4-T3 conversion |
High | High | High | Peripheral thyroid hormone resistance |
Low | Low | Low | Pituitary thyroid deficiency or recent withdrawal of thyroxine after excessive replacement therapy |