Vaccination and antibody status of exposed workers*		Treatment
		Source HbsAg† positive		Source HbsAg†negative	Source unknown or not available for testing
Unvaccinated		HBIG‡ x 1 and initiate HB vaccine series.§		Initiate HB vaccine series.		Initiate HB vaccine series.
Previously vaccinated
	Known responder‖	No treatment		No treatment	No treatment
	Known nonresponder¶	HBIG x 1 and initiate revaccination or HBIG x 2.#		No treatment	If known high-risk source, treat as if source were HbsAg positive.
	Antibody response unknown	Test exposed person for anti-HBs.**		No treatment	Test exposed person for anti-HBs.
			1. If adequate,‖ no treatment is necessary.			1. If adequate,§ no treatment necessary.
			2. If inadequate, administer HBIG x 1and vaccine booster.			2. If inadequate,§ administer vaccine and booster and recheck titer in one to two months.