Risk category	LDL goal	LDL level at which to initiate TLC	LDL level at which to consider drug therapy
CHD or CHD risk equivalent (10-year risk >20 percent)	<100 mg/dL(2.60 mmol/L)	≥ 100 mg/dL	≥ 130 mg/dL (at 100 to 129 mg/dL, drug optional)*
2 or more risk factors (10-year risk <20 percent)	<130 mg/dL (3.35 mmol/L)	≥ 130 mg/dL	≥ 130 mg/dL for 10-year risk of 10 to 20 percent; 160 mg/dL for 10-year risk of <10 percent
0 to 1 risk factor†	<160 mg/dL (4.15 mmol/L)	≥ 160 mg/dL	≥ 190 mg/dL (at 160 to 189 mg/dL, LDL-lowering drug optional)