Triple therapy |
1. Omeprazole (Prilosec), 20 mg two times daily | $260 (LAC†) | Twice-daily dosing | Fewer significant side effects, but more abnormal taste versus other regimens |
| | or | | | |
| Lansoprazole (Prevacid), 30 mg two times daily | 195 (LAC†‡) | | |
| | plus | | | |
| Metronidazole (Flagyl), 500 mg two times daily | 200 (OAC) | | |
| | or | | | |
| Amoxicillin, 1 g two times daily | 194 (LMC) | | |
| | plus | | | |
| Clarithromycin (Biaxin), 500 mg two times daily | 199 (OMC) | | |
2. Ranitidine bismuth citrate (Tritec), 400 mg twice daily | 118 (RCT) | Twice-daily dosing | Increased diarrhea versus other regimens |
| | plus | | | |
| Clarithromycin, 500 mg twice daily | | | |
| | or | | | |
| Metronidazole, 500 mg twice daily | 136 (RCA) | | |
| | plus | | | |
| Tetracycline, 500 mg twice daily | 73 (RMT) | | |
| | or | | | |
| Amoxicillin, 1 g twice daily | 92 (RMA) | | |
Quadruple therapy |
3. Bismuth subsalicylate (Pepto Bismol), 525 mg four times daily/2 tablets four times daily | 142 (BMT§ plus H2R†) | 18 pills daily | More side effects; increased nausea versus other regimens |
| | plus | | | |
| Metronidazole, 250 mg four times daily | 87 (BMT [separately] plus H2R†) | | |
| | plus | | | |
| Tetracycline, 500 mg four times daily | | | |
| | plus | | | |
| H2RA for 28 days | | | |
4. Bismuth subsalicylate, 525 mg four times daily/2 tablets four times daily | 206 (BMT plus PPI) | 18 pills daily | Increased nausea |
| | plus | | | |
| Metronidazole, 250 mg four times daily | | | |
| | plus | | | |
| Tetracycline, 500 mg four times daily | 153 (BMT separately] plus PPI) | | |
| | plus | | | |
| PPI for 14 days | | | |