Immediately after birth
Prenatal diagnosis warranting special care
Significant prematurity (less than 34 to 35 weeks' gestation)
Intrauterine growth restriction
Twin-to-twin transfusion syndrome
Clinically significant congenital anomalies
Rh sensitization
Maternal conditions (e.g., drug use, diabetes)
Maternal medications resulting in neonatal depression (e.g., opiates for pain control, magnesium sulfate)
Risk factors for sepsis (e.g., clinical chorioamnionitis)
Delivery complications
Asphyxia, low 5-minute Apgar score, prolonged resuscitation
Placental abruption, placenta previa, vasa previa
Early postnatal period
Cardiorespiratory
	Poor peripheral perfusion (slow capillary refill, low blood pressure)
	Respiratory distress (grunting, tachypnea more than 60 breaths per minute, intercostal retractions)
	Cyanosis (congenital heart disease)
	Apnea and/or cyanotic episodes
Gastrointestinal
	Feeding intolerance
	No meconium passage by 24 hours of age
	Bilious vomiting
Neurologic
	Seizures
	Signs of drug withdrawal
	Poor tone
	Lethargy
Jaundice
	Any visible jaundice at less than 24 hours of age
	Clinically significant, age-specific hyperbilirubinemia
	Rate of rise of bilirubin more than 0.5 mg per dL (8.55 μmol per L) per hour
Metabolic and others
	Temperature instability (consistently below 36.4°C [97.5°F])
	Low blood glucose level (less than 45 mg per dL [2.5 mmol per L]) or high blood glucose level (more than 180 mg per dL [10.0 mmol per L])
	Petechiae and purpura
	Clinically significant congenital anomalies