In the absence of unequivocal hyperglycemia with acute metabolic decompensation, these criteria should be confirmed by repeated testing on different days to establish the diagnosis of diabetes mellitus.
1. Symptoms of diabetes plus casual plasma glucose level 200 mg per dL (11.1 mmol per L). Casual is defined as any time of day without regard to time since last meal. The classic symptoms of diabetes include polyuria, polydipsia, and unexplained weight loss.
2. Fasting plasma glucose level 126 mg per dL (7.0 mmol per L). Fasting is defined as no caloric intake for at least eight hours.
3. Two-hour plasma glucose level 200 mg per dL during an oral glucose-tolerance test. The test should be performed using a glucose load containing the equivalent of 75 g of anhydrous glucose dissolved in water. This test is not recommended for routine clinical use.