Drug name | FDA pregnancy risk classification by trimester (1st/2nd/3rd) | Drug class | Crosses placenta? | Use in pregnancy |
---|---|---|---|---|
Kaolin and pectin (Kaopectate) | B/B/B | Antidiarrheal | No | Antidiarrheal of choice (not absorbed) |
Bismuth subsalicylate (Pepto Bismol) | C/C/D | Antidiarrheal | Yes | Not recommended (salicylate absorption) |
Loperamide (Imodium) | B/B/B | Antidiarrheal | Not known | Probably safe* |
Atropine/diphenoxylate (Lomotil) | C/C/C | Antidiarrheal | Not known | Not recommended (adverse animal studies) |