Parasite
TreatmentPrevention
Enterobius vermicularisPrimary: Mebendazole (Vermox), 100 mg orally once
Secondary: Pyrantel pamoate (Pin-Rid), 11 mg per kg (maximum of 1 g) orally once; or
albendazole (Valbazen), 400 mg orally once
If persistent, repeat treatment in two weeks.
Do not give to children younger than two years.
Treat household contacts.
Clean bedrooms, bedding.
Giardia lambliaAdults: Metronidazole (Flagyl), 250 mg orally three times daily for five to seven days
Pregnant women with mild symptoms: consider deferring treatment until after delivery.
Pregnant women with severe symptoms: paromomycin (Humatin), 500 mg orally four times daily for seven to 10 days; metronidazole is acceptable.
Children: albendazole, 400 mg orally for five days
Asymptomatic carriers in developed countries: treat using regimen for adults or children.
Asymptomatic carriers in developing countries: not cost-effective to treat because of high reinfection rate.
Use proper sewage disposal and water treatment (flocculation, sedimentation, filtration, and chlorination).
Consume only bottled water in endemic areas.
Water treatment options:
Boil water for one minute
Heat water to 70 C (158 F) for 10 minutes
Portable camping filter
Iodine purification tablets for eight hours
Daycare centers:
Proper disposal of diapers
Proper and frequent handwashing
Ancylostoma duodenale, Necator americanusAlbendazole, 400 mg orally once
Mebendazole, 100 mg orally twice daily for three days
Pyrantel pamoate, 11 mg per kg (maximum of 1 g) once
Iron supplementation is beneficial even before diagnosis or treatment initiation.
Packed red blood cells (as needed) can minimize risk of volume overload in severely hypoproteinemic patients.
Confirm eradication with follow-up stool examination two weeks after discontinuation of treatment.
Use proper and continued shoe wear. Use proper sewage disposal.
Entamoeba histolyticaIntestinal disease: use both luminal amebicide (for cysts) and tissue amebicide (for trophozoites)Use proper sanitation to eradicate cyst carriage.
Avoid eating unpeeled fruits and vegetables.
Drink bottled water.
Use iodine disinfection of nonbottled water.
Luminal:
Iodoquinol (Yodoxin), 650 mg orally three times daily for 20 days
or
Paromomycin, 500 mg orally three times daily for seven days
or
Diloxanide furoate (Furamide), 500 mg orally three times daily for 10 days (available from CDC)
Tissue:
Metronidazole, 750 mg orally three times daily for 10 days
Liver abscess:
Metronidazole, 750 mg orally three times daily for five days, then paromomycin, 500 mg three times daily for seven days
or
Chloroquine (Aralen), 600 mg orally per day for two days, then 200 mg orally per day for two to three weeks (higher relapse rates)
Aspirate if:
Pyogenic abscess is ruled out; there is no response to treatment in three to five days; rupture is imminent; pericardial spread is imminent