Interferon beta-1a (Avonex) | 30 mcg IM once weekly | Influenza-like symptoms | $1,278 |
| | Monitoring of CBC and liver function | |
Interferon beta-1a (Rebif) | 22 to 44 mcg SC three times weekly | Influenza-like symptoms and injection-site reactions | 1,517 |
| | Monitoring of CBC and liver function | |
Interferon beta-1b (Betaseron) | 0.25 mg SC every other day | Influenza-like symptoms and injection-site reactions | 1,403 |
| | Monitoring of CBC and liver function | |
Glatiramer (Copaxone) | 20 mg SC once daily | Injection-site reactions and, rarely, a benign systemic reaction | 1,261 |
| | Requires no blood monitoring | |
Mitoxantrone (Novantrone) | 5 to 12 mg per m2 IV every 3 months | Mild chemotherapy-related side effects, cumulative cardiotoxicity, small increased risk of leukemia | 1,453 |