Insulin		Onset	Peak (hours)	Usual effective duration (hours)	Usual maximum duration (hours)	Cost*
Bolus or mealtime insulin
	Aspart (NovoLog)	5 to 10 minutes	1 to 3	3 to 5	4 to 6	$59
	Lispro (Humalog)	< 15 minutes	0.5 to 1.5	2 to 4	4 to 6	59
	Regular (Humulin R, Novolin R)	30 to 60 minutes	2 to 3	3 to 6	6 to 10	28
Basal insulin
	NPH (Humulin N, Novolin N)	2 to 4 hours	4 to 10	10 to 16	14 to 18	28
	Lente (insulin zinc suspension)	3 to 4 hours	4 to 12	12 to 18	16 to 20
	Ultralente (extended insulin zinc suspension)	6 to 10 hours	Peakless	18 to 20	20 to 24	28
	Glargine (Lantus)	1 hour, 6 minutes	Peakless	24	24	51
Combinations
	50% NPH/50% regular	30 to 60 minutes	Dual	10 to 16	14 to 18
	70% NPH/30% regular (Humulin R 70/30, Novolin R 70/30)	30 to 60 minutes	Dual	10 to 16	14 to 18	28
	75% NPL/25% lispro (Humalog 75/25)	< 15 minutes	Dual	10 to 16	14 to 18	59†
	70% APS/30% aspart (NovoLog Mix 70/30)	10 to 20 minutes	2.4 ± 0.80	24	24	59