| Neuropathic pain | Non-neuropathic pain | ||||
|---|---|---|---|---|---|
| Drug | Trigeminal neuralgia | Diabetic neuropathy or postherpetic neuralgia | Fibromyalgia | Low back or other pain | |
| Antidepressants | |||||
| Amitriptyline (Elavil)4–8 | 1 | 1 | 2 | ||
| Fluoxetine (Prozac)9 | 3 | ||||
| Bupropion (Wellbutrin)10 | 2 | ||||
| Venlafaxine (Effexor)11 | 2 | ||||
| Duloxetine (Cymbalta)12,13 | 1 | 1 | |||
| Antiepileptics | |||||
| First generation | |||||
| Carbamazepine (Tegretol)14 | 1 | 3 | |||
| Phenytoin (Dilantin)14 | 3 | ||||
| Second generation | |||||
| Gabapentin (Neurontin)15,16 | 1 | ||||
| Lamotrigine (Lamictal)17* | 3 | ||||
| Pregabalin (Lyrica)18,19† | 2 | 2 | |||