MedicationDosage formDosage*
Inhaled corticosteroids (see Table 4)
Long-acting inhaled beta2 agonists†
Formoterol (Foradil Aerolizer)DPI: 12 mcg per single-use capsule1 capsule every 12 hours
Salmeterol (Serevent)MDI: 21 mcg per puff1 to 2 puffs every 12 hours
DPI: 50 mcg per blister1 blister every 12 hours
Combined medication
Fluticasone/salmeterol (Advair Diskus)DPI: 100, 250, or 500 mcg of fluticasone with 50 mcg of salmeterol1 inhalation twice daily; dosage depends on severity of asthma
Cromolyn and nedocromil
Cromolyn (Intal)MDI: 1 mg per puff1 to 2 puffs 3 to 4 times daily
Nebulizer solution: 20 mg per ampule1 ampule 3 to 4 times daily
Nedocromil (Tilade)MDI: 1.75 mg per puff1 to 2 puffs 2 to 4 times daily
Leukotriene modifiers
Montelukast (Singulair)4- or 5-mg chewable tablets, 4-mg packet of oral granules, 10-mg tabletsAge 12 to 23 months: 4 mg oral granules at bedtime
Age 2 to 5 years: 4 mg at bedtime
Age 6 to 14 years: 5 mg at bedtime
Older than 14 years: 10 mg at bedtime
Zafirlukast (Accolate)10- and 20-mg tabletsAge 7 to 11 years: 20 mg daily in divided doses (i.e., one 10-mg tablet twice daily)
12 years and older: 20 mg twice daily
Methylxanthines‡
TheophyllineLiquids, sustained-release tablets, and capsulesStarting dosage is 10 mg per kg per day:
Usual maximums: Age < 1 year: (0.2 x [age in weeks]) + 5 = mg per kg per day Age ≥1 year: 16 mg per kg per day