Generic name	Brand name	Initial dosage	Targe dosage range*	Common adverse effects	Cost for brand name drug (cost for generic)
Levodopa plus carbidopa	Sinemet	10 mg carbidopa with 100 mg levodopa; 25 mg carbidopa with 100 mg levodopa; 25 mg carbidopa with 250 mg levodopa (medication three times per day)†	Increase by one tablet every day or every other day to a maximum of eight tablets per day	Dyskinesia, dystonia, hallucinations, hyperkinesia, dizziness, fatigue, abdominal pain, constipation, diarrhea, nausea, vomiting, urine discoloration, cardiac abnormalities, orthostatic hypotension	$84 ($72 to $85) per month
	Sinemet CR	50 mg carbidopa with 200 mg levodopa two times per day	Increase by one tablet every three days to a maximum of eight tablets per day	Same as above	$121 per month
Levodopa plus carbidopa and entacapone	Stalevo	12.5 mg carbidopa with 50 mg levodopa and 200 mg entacapone two times per day	Increase slowly to a maximum of eight tablets per day	Same as above	$198 per month
Dopamine agonists
Bromocriptine	Parlodel	1.25 mg two times per day	Adjust every two weeks up to 5 to 20 mg two times per day	Nausea, headache, dizziness	$106 ($66 to $70) per month
Pramipexole	Mirapex	0.125 mg three times per day	Adjust every week up to 1.5 mg three times per day	Dizziness, somnolence, hallucinations, nausea, edema	$107 per month
Ropinirole	Requip	0.25 mg three times per day	Adjust every week up to 1 mg three times per day	Dizziness, somnolence, nausea, hallucinations, edema	$135 per month
MAOI-B
Selegiline	Eldepryl	5 mg at breakfast and lunch	No dosage titration required	Nausea, dizziness, abdominal pain, confusion, hallucinations	$81 per month