Clinical recommendation	Evidence rating	References
Patients with asymptomatic diverticulosis should eat a high-fiber diet to prevent symptomatic diverticular disease.	C	⁶
All patients with symptomatic diverticular disease should undergo colonoscopy to exclude underlying neoplasm.	C	⁶
Patients with suspected diverticulitis should undergo computed tomography with intravenous and oral contrast rather than other diagnostic modalities such as endoscopy or contrast radiography.	C	^13,17
To provide adequate coverage of gram-negative rods and anaerobic bacteria, patients with acute diverticulitis treated as outpatients should receive metronidazole (Flagyl) combined with a quinolone or with trimethoprim-sulfamethoxazole (Bactrim, Septra) or amoxicillin-clavulanate (Augmentin).	C	⁶
Patients hospitalized with acute diverticulitis should receive metronidazole or clindamycin (Cleocin) combined with an aminoglycoside, a monobactam, or a third-generation cephalosporin.	C	⁶