The Agency for Healthcare Research and Quality (AHRQ) has published an updated version of evidence-based clinical guidelines from the U.S. Preventive Services Task Force (USPSTF). The Guide to Clinical Preventive Services 2005 includes the USPSTF’s recommendations on prevention and early detection of cancer; heart and vascular diseases; infectious diseases; injury and violence; mental health conditions and substance abuse; metabolic, nutritional, and endocrinologic conditions; musculoskeletal conditions; and obstetric and gynecologic conditions. Free single copies of the new guide are available online athttp://www.ahrq.gov/clinic/pocketgd.htm or by calling the AHRQ Publications Clearinghouse at (800) 358–9295.