MedicationTypical dosageCost per month*Main adverse effects
Amitriptyline†Weight gain, dry mouth, sedation
Generic10 to 150 mg per day$7
DivalproexLiver toxicity, sedation, nausea, weight gain, tremor, teratogenicity, possible drug toxicity
Depakote250 to 500 mg twice per day78
Extended-release (Depakote ER)500 to 1,000 mg per day69
PropranololFatigue, exercise intolerance
Generic80 to 240 mg per day, in three or four divided doses9
Sustained-release (Inderal LA)80 to 240 mg per day46
TimololFatigue, exercise intolerance
Generic10 to 15 mg twice per day23
BlocadrenAs generic37
TopiramateParesthesia, fatigue, nausea
Topamax50 mg twice per day (titrate from 15 to 25 mg)211
Valproic acid†Liver toxicity, sedation, nausea, weight gain, tremor, teratogenicity, possible drug toxicity
Generic250 to 500 mg twice per day30–60
DepakeneAs generic136