Clinical recommendationEvidence ratingReferences
Prednisone (40 to 60 mg daily) is recommended for patients with subacute thyroiditis when nonsteroidal anti-inflammatory drugs fail to provide pain relief.C1
Treatment for subclinical hypothyroidism may be initiated in patients with a thyroid-stimulating hormone level greater than 10 mcU per mL (10 mU per L).B11,12
Thyroid hormone replacement should be initiated in women with an elevated thyroid-stimulating hormone level who are pregnant or attempting to become pregnant.B13
Screening for antithyroid peroxidase antibodies should be considered in women who are at high risk and are pregnant.B16,18