| Patients with lichen sclerosus should be evaluated for vulvar malignancy because they are at higher risk for squamous cell carcinoma. | C | 9, 10 | Studies of large groups of women |
| Lichen sclerosus should be treated with a high-potency steroid ointment, such as clobetasol propionate 0.05% (Temovate), to alleviate symptoms, prevent architectural damage, and reverse histologic changes. | B | 31–33 | Consistent findings from randomized controlled trial and descriptive cohort study |
| Vaginal hydrocortisone suppositories are effective for treating erosive vulvovaginal lichen planus. | B | 42 | Prospective observational trial |
| Breaking the itch-scratch cycle is fundamental to the treatment of lichen simplex chronicus. | C | 20,22 | Expert consensus |