PreparationDrugDosages (mg per day)
Estrogen*
OralConjugated estrogens (Premarin)0.3, 0.45, 0.625, 0.9, 1.25
Transdermal17β-estradiol (Estrace)0.5, 1.0, 2.0
17β-estradiol (Alora)0.025, 0.05, 0.075, 0.1 (patch applied twice weekly)
17β-estradiol (Climara)0.025, 0.0375, 0.05, 0.075, 0.1 (patch applied weekly)
VaginalEstradiol acetate (Femring vaginal insert†)0.05, 0.1 (inserted every 90 days)
Progestogen
OralMPA (Provera)2.5, 5.0, 10.0
Micronized progesterone (Prometrium)100, 200 (in peanut oil)
VaginalProgesterone (Prochieve 4%)45
Combined preparation
Oral sequential‡Conjugated estrogens and MPA (Premphase)0.625 conjugated estrogens plus 5.0 MPA
Oral continuous§Conjugated estrogens and MPA (Prempro)0.625 conjugated estrogens plus 2.5 or 5.0 MPA;
or
0.45 conjugated estrogens plus 2.5 MPA;
or
0.3 or 0.45 conjugated estrogens plus 1.5 MPA
Transdermal continuous§17β-estradiol–norethindrone acetate (Activella)1.0 estradiol plus 0.5 norethindrone
17β-estradiol–levonorgestrel (Climara Pro)0.045 estradiol plus 0.015 levonorgestrel (patch applied weekly)
17β-estradiol–norethindrone acetate (Combipatch)0.05 estradiol plus 0.14 or 0.25 norethindrone (patch applied twice weekly)