ClassGeneric (brand)Standard dosageMaximal dosage (mg per day)Approximate monthly cost*
Salicylic acidsAspirin325 to 650 mg every four hours4,000$3 for 325-mg dose
Diflunisal (Dolobid)500 mg two times daily1,500$77 (generic) and $73 (brand)
Salsalate1,500 mg two times daily3,000$27 to $40
Choline magnesium trisalicylate1,500 mg two times daily3,000$44 to $54
Acetic acidsDiclofenac potassium (Cataflam)50 mg three times daily200$140 to $173 (generic) and $327 (brand)
Diclofenac sodium, delayed release (Voltaren)50 mg two or three times daily200$85 to $98 (generic) and $192 (brand) for 50 mg two times daily
Etodolac200 to 400 mg two or three times daily1,200$77 to $90 for 200 mg two times daily
Indomethacin (Indocin)25 to 50 mg three times daily200$5 to $30 (generic) and $80 (brand) for 25-mg dose
Indomethacin, extended release (Indocin SR)25 to 50 mg one or two times daily150$60 (generic) and $84 (brand) for 25 mg once daily
Sulindac (Clinoril)200 mg two times daily400$72 to $80 (generic) and $86 (brand)
Tolmetin200 to 600 mg three times daily1,800$67 for 200-mg dose
OxicamMeloxicam (Mobic)7.5 to 15 mg once daily15$95 to $108 (generic) and $117 (brand) for 7.5-mg dose
Piroxicam (Feldene)20 mg once daily20$79 to $104 (generic) and $133 (brand)
Propionic acidsIbuprofen600 mg four times daily or 800 mg three times daily2,400$30 to $35 (generic) and $48 for 600-mg dose
Ketoprofen50 to 100 mg three times daily300$60 to $204 for 50-mg dose
Naproxen (Naprosyn)250 to 500 mg two times daily1,500$42 to $72 (generic) and $70 (brand) for 250-mg dose
Naproxen sodium (Anaprox)275 to 550 mg two times daily1,650$50 to $53 (generic) and $63 (brand) for 275-mg dose
Oxaprozin (Daypro)1,200 mg once daily1,800$108 to $164 (generic) and $157 (brand)
Anthranilic acidMeclofenamate50 to 100 mg four times daily400$220 for 50-mg dose
Cyclooxygenase-2 inhibitorCelecoxib (Celebrex)200 mg two times daily400$240
Nonacidic agentNabumetone1,000 to 2,000 mg one or two times daily2,000$77 to $98 (generic) and $107 (brand) for 1,000 mg once daily