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Am Fam Physician. 2015;91(5):320-322

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Clinical Question

Does obesity in children increase the risk of joint injuries?

Evidence-Based Answer

Lower extremity injuries are 18% more likely in overweight children, 24% more likely in obese children, and 34% more likely in extremely obese children when compared with normal weight peers. The risk of lower extremity fractures is also increased by 17% in overweight children, 23% in obese children, and 45% in extremely obese children. Extremely obese prepubertal children have the greatest fracture risk at 2.2 times that of normal weight peers. Overweight and obese children do not have an increased risk of upper extremity injuries. Overweight children are also more likely to have persistent pain and swelling six months after an ankle sprain.

Evidence Summary

A large, retrospective, cross-sectional cohort study examined rates of upper and lower extremity injuries over two years in more than 910,000 children two to 19 years of age.1 The children were stratified by weight. Compared with normal weight peers, children had an increased risk of lower extremity injury if they were overweight (body mass index [BMI] in the 85th to 95th percentile; odds ratio [OR] = 1.18; 95% confidence interval [CI], 1.15 to 1.20), obese (BMI in the 95th percentile to 1.2 × 95th percentile; OR = 1.24; 95% CI, 1.20 to 1.27), or extremely obese (BMI greater than 1.2 × 95th percentile; OR = 1.34; 95% CI, 1.30 to 1.39). Injuries included fractures (16% of patients); sprains of the hip, thigh, knee, ankle, or foot (57%); and dislocations (4%). Other patients had lower extremity pain without a specific diagnosis. There was no association between obesity and upper extremity injuries or pain. Being underweight (BMI less than 5th percentile) was protective for injuries. Underweight children had fewer upper extremity (OR = 0.81; 95% CI, 0.75 to 0.86) and lower extremity (OR = 0.61; 95% CI, 0.57 to 0.66) injuries compared with normal weight children.

Another study reviewed the same database and specifically focused on fracture risk.2 There was an increased risk of lower extremity fractures in children who were overweight (OR = 1.17; 95% CI, 1.10 to 1.25), moderately obese (OR = 1.23; 95% CI, 1.15 to 1.32), and extremely obese (OR = 1.45; 95% CI, 1.33 to 1.58) compared with normal weight children. The highest correlation between obesity and fracture was in children six to 11 years of age (overweight, OR = 1.58; 95% CI, 1.41 to 1.78; moderately obese, OR = 1.63; 95% CI, 1.44 to 1.84; and extremely obese, OR = 2.23; 95% CI, 1.92 to 2.59). In children two to five years of age and in those 12 to 19 years of age, the correlation was significant only in extremely obese children (OR = 1.89; 95% CI, 1.28 to 2.81; and OR = 1.10; 95% CI, 1.03 to 1.24, respectively).

Another large, retrospective, cross-sectional cohort study showed similar results in more than 23,000 children three to 14 years of age presenting to a pediatric emergency department with a traumatic injury.3 Obese children (BMI greater than 95th percentile) were more likely to present with lower extremity injuries (OR = 2.01; 95% CI, 1.85 to 2.17), but not upper extremity injuries (OR = 1.00; 95% CI, 0.93 to 1.08) compared with nonobese peers.

A retrospective, cross-sectional cohort study surveyed 2,459 Dutch families for injuries in their children within the prior two weeks.4 Investigators determined body habitus using self-reported height and weight. Overweight and obese children reported higher rates of recent lower extremity injuries (OR = 1.62; 95% CI, 1.09 to 2.41) but not upper extremity injuries (OR = 1.03; 95% CI, 0.36 to 2.98) compared with normal weight children. Obesity was not associated with more physician visits for musculoskeletal problems within the prior year.

A prospective cohort study enrolled 199 children eight to 18 years of age presenting to the emergency department with an acute ankle sprain.5 The patients were surveyed about their health status six months after the initial injury. Children with BMIs greater than the 85th percentile were more likely to report persistent pain with activity (OR = 2.25; 95% CI, 1.25 to 4.02) and persistent swelling or weakness (OR = 2.4; 95% CI, 1.28 to 4.52) than children with lower BMIs. Children with BMIs greater than the 95th percentile had similar outcomes.

Recommendations from Others

There are no expert recommendations specifically to reduce the risk of lower extremity injuries in children who are overweight or obese.

Copyright Family Physicians Inquiries Network. Used with permission.

Clinical Inquiries provides answers to questions submitted by practicing family physicians to the Family Physicians Inquiries Network (FPIN). Members of the network select questions based on their relevance to family medicine. Answers are drawn from an approved set of evidence-based resources and undergo peer review. The strength of recommendations and the level of evidence for individual studies are rated using criteria developed by the Evidence-Based Medicine Working Group (https://www.cebm.net).

The complete database of evidence-based questions and answers is copyrighted by FPIN. If interested in submitting questions or writing answers for this series, go to https://www.fpin.org or email questions@fpin.org.

Copyright © Family Physicians Inquiries Network. Used with permission.

This series is coordinated by John E. Delzell Jr., MD, MSPH, associate medical editor.

A collection of FPIN’s Clinical Inquiries published in AFP is available at https://www.aafp.org/afp/fpin.

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