Symptoms (to the time of diagnosis)	Score
	0*	1*	2	3	4
Epistaxis	None/trivial	More than five per year or lasting longer than 10 minutes	Consultation only†	Packing, cauterization, or antifibrinolytic therapy	Blood transfusion, replacement therapy (use of hemostatic blood components and recombinant activated factor VII), or desmopressin therapy
Cutaneous symptoms	None/trivial	At least five bruises (> 1 cm) in exposed areas	Consultation only†	Extensive	Spontaneous hematoma requiring blood transfusion
Bleeding from minor wounds	None/trivial	More than five per year or lasting longer than 10 minutes	Consultation only†	Surgical hemostasis	Blood transfusion, replacement therapy, or desmopressin therapy
Oral cavity symptoms	None/trivial	Present	Consultation only†	Surgical hemostasis or antifibrinolytic therapy	Blood transfusion, replacement therapy, or desmopressin therapy
Gastrointestinal bleeding	None/trivial	Present (not associated with ulcer, portal hypertension, hemorrhoids, or angiodysplasia)	Consultation only†	Surgical hemostasis or antifibrinolytic therapy	Blood transfusion, replacement therapy, or desmopressin therapy
Hematuria	None/trivial	Present (macroscopic)	Consultation only†	Surgical hemostasis or iron therapy	Blood transfusion, replacement therapy, or desmopressin therapy
Tooth extraction	None/trivial	Reported in 25% or less of all procedures; no intervention‡	Reported in more than 25% of all procedures; no intervention‡	Resuturing or packing	Blood transfusion, replacement therapy, or desmopressin therapy
Surgery	None/trivial	Reported in 25% or less of all procedures; no intervention‡	Reported in more than 25% of all procedures; no intervention‡	Surgical hemostasis or antifibrinolytic therapy	Blood transfusion, replacement therapy, or desmopressin therapy
Menorrhagia	None/trivial	Consultation only,† changing pads more frequently than every two hours, clotting and flooding, or score higher than 100 on pictorial blood loss assessment chart§	Missed work/school more than twice per year; antifibrinolytic, hormone, or iron therapy	Combined antifibrinolytic and hormone therapy, or present since menarche and longer than 12 months	Acute menorrhagia requiring hospital admission and emergency treatment; blood transfusion, replacement therapy, or desmopressin required; or dilation and curettage, endometrial ablation, or hysterectomy required
Postpartum hemorrhage	None/trivial	Consultation only,† oxytocin (Pitocin) use, or lochia lasting longer than six weeks	Iron or antifibrinolytic therapy	Blood transfusion, replacement therapy, desmopressin therapy, or requiring examination under anesthesia and/or the use of uterine balloon/package to tamponade the uterus	Any procedure requiring critical care or surgical intervention (e.g., hysterectomy, internal iliac artery ligation, uterine artery embolization, uterine brace sutures)
Muscle hematomas	Never	Post-trauma, no therapy	Spontaneous, no therapy	Spontaneous or traumatic, requiring desmopressin or replacement therapy	Spontaneous or traumatic, requiring surgical intervention or blood transfusion
Hemarthrosis	Never	Post-trauma, no therapy	Spontaneous, no therapy	Spontaneous or traumatic, requiring desmopressin or replacement therapy	Spontaneous or traumatic, requiring surgical intervention or blood transfusion
Central nervous system bleeding	Never	—	—	Subdural, any intervention	Intracerebral, any intervention
Other bleeding¶	None/trivial	Present	Consultation only†	Surgical hemostasis, antifibrinolytic therapy	Blood transfusion, replacement therapy, or desmopressin therapy