| Acupuncture | Chronic low back pain | First-line | Should be performed by a licensed practitioner |
| Coenzyme Q10 | Heart failure | Adjunctive | Dosage is 100 mg three times per day |
| Exercise | Anxiety | First-line | May be helpful in patients with diagnosed anxiety disorders, those with chronic illness without diagnosed anxiety, and those with depression; aerobic exercise is best studied; 30 minutes three to five times per week seems to be most effective |
| Fish oil | Hypertriglyceridemia | First-line | Lowers triglyceride levels, but unclear if it reduces cardiovascular events; dosage is 4 g of combined eicosapentaenoic acid/docosahexaenoic acid per day; may have minor gastrointestinal adverse effects; no significant medication interactions |
| Ginkgo biloba | Dementia | First-line | Use extract standardized to 22% to 27% ginkgo flavonoids; typical dosage is 240 mg per day |
| Mind-body interventions | Insomnia | First-line | Cognitive behavior therapy is most effective; alternatives include meditation, hypnosis, yoga, and tai chi |
| Probiotics | Prevention of antibiotic-associated diarrhea | First-line | Start within one to three days of starting antibiotics, and continue for one week after stopping; dosage is 5 to 10 billion colony-forming units per day for children, 10 to 20 billion colony-forming units per day for adults; multiple strains available; not clear which are most effective |
| St. John's wort | Depression | First-line | Use in mild to moderate depression rather than severe depression; do not use in combination with selective serotonin reuptake inhibitors; significant potential for interactions; occasional gastrointestinal adverse effects |
