Side effect	Medicine
Bleeding problems	Tipranavir (brand name: Aptivus) may cause bleeding in the head
Body fat changes, lactic acidosis, pancreatitis	Didanosine (brand name: Videx)
	Stavudine (brand name: Zerit)
	Zidovudine (brand name: Retrovir; also found in Combivir and Trizivir)
Bone marrow problems	Zidovudine (brand name: Retrovir; also found in Combivir and Trizivir)
Bone problems	Boosted protease inhibitors
	Efavirenz (brand name: Sustiva; also found in Atripla)
	Tenofovir disoproxil fumarate (brand name: Viread; also found in Truvada, Atripla, Complera, and Stribild)
Cholesterol problems	All protease inhibitors
	Abacavir (brand name: Ziagen; also found in Epzicom and Triumeq)
	Efavirenz (brand name: Sustiva; also found in Atripla)
	Elvitegravir/cobicistat (found in Stribild and Genvoya)
	Stavudine (brand name: Zerit)
Diabetes	Many protease inhibitors
Increased risk of heart disease	Possibly abacavir (brand name: Ziagen; also found in Epzicom and Triumeq)
	Lopinavir/ritonavir (brand name: Kaletra)
Kidney stones	Atazanavir (brand name: Reyataz; also found in Evotaz)
	Darunavir (brand name: Prezista; also found in Prezcobix)
	Fosamprenavir (brand name: Lexiva)
Other kidney problems	Atazanavir (brand name: Reyataz; also found in Evotaz)
	Tenofovir disoproxil fumarate (brand name: Viread; also found in Truvada, Atripla, Complera, and Stribild)
Liver problems	All ART medicines can affect the liver, but especially didanosine (brand name: Videx), nevirapine (brand name: Viramune), stavudine (brand name: Zerit), and zidovudine (brand name: Retrovir; also found in Combivir and Trizivir)
Mood and sleeping problems	All integrase strand transfer inhibitors
	Efavirenz (brand name: Sustiva; also found in Atripla)
	Rilpivirine (brand name: Edurant; also found in Complera and Odefsey)
Muscle pain	All integrase strand transfer inhibitors, especially raltegravir (brand name: Isentress) and zidovudine (brand name: Retrovir; also found in Combivir and Trizivir)
Nail color changes	Emtricitabine (brand name: Emtriva; also found in Truvada, Descovy, Atripla, Complera, Odefsey, Stribild, and Genvoya)
	Zidovudine (brand name: Retrovir; also found in Combivir and Trizivir)
Nerve problems	Older NRTIs such as didanosine (brand name: Videx), stavudine (brand name: Zerit), and zidovudine (brand name: Retrovir; also found in Combivir and Trizivir)
Upset stomach, loose stools	All ART medicines can cause gastrointestinal problems at first
	Some protease inhibitors can cause long-term stomach upset or changes in stools