Type of testosterone (brand)		Dosage and frequency	Common starting dosage	Cost*	Comments
Buccal testosterone (Striant)		30 mg twice daily	30 mg twice daily	NA ($620) for 60 tablets	May alter taste or irritate oral mucosa
Injectable/intramuscular
	Testosterone cypionate (Depo-Testosterone)	50 to 400 mg every one to four weeks	100 mg weekly or 200 mg every two weeks	200 mg per mL: $115 ($130) for one 10-mL vial	—
	Testosterone enanthate (Delatestryl)	50 to 400 mg every one to four weeks	100 mg weekly or 200 mg every two weeks	200 mg per mL: $80 ($100) for one 5-mL vial	Serum levels tend to have peaks and troughs
	Testosterone undecanoate (Aveed)	750-mg initial dose and another 750 mg four weeks later, then 750 mg every 10 weeks	Two doses four weeks apart, then every 10 weeks	NA ($995) per 750-mg dose	Special prescriber registration required because of risk of anaphylaxis and pulmonary oil microembolism
Intranasal gel (Natesto)		33 mg; one actuation (11 mg) in each nostril three times daily	Three times daily	NA ($235) for one inhaler	Adverse effects include headache, nasopharyngeal and upper respiratory symptoms
Pellets (Testopel)		150 to 450 mg every three to six months	150 mg every three months	NA ($950) for 10 75-mg pellets	—
Transdermal gel
	Androgel 1% or 1.62%	50 to 100 mg daily	50 mg daily	1% gel: $310 ($560) for 30 50-mg doses	Possible to transfer from one person to another; risk of virilization of exposed women and children
	Fortesta	10 to 70 mg daily	40 mg daily	$350 ($450) for one pump
	Testim 1%	50 to 100 mg daily	50 mg daily	$400 ($600) for 30 50-mg doses
Transdermal patch (Androderm)		2 to 4 mg daily	2 mg daily	NA ($550) for 30 4-mg patches	Skin rash common; patients should be advised to rotate application sites
Transdermal solution (Axiron)		30 to 120 mg daily	60 mg daily	30 mg: NA ($615) for one bottle	Applied to axillary area similar to deodorant; risk of transfer to others as with gel forms