Heidi L. Gaddey, Kathryn K. Holder
Unintentional weight loss in people older than 65 years is associated with increased morbidity and mortality. Treatment should focus on feeding assistance, addressing contributing medications, providing appealing foods, and social support.
Roland Grad, Mark H. Ebell
The annual installment of this series summarizes the top studies of 2020. These studies were summarized as POEMs (patient-oriented evidence that matters) and were highly rated by Canadian Medical Association members for their clinical relevance. This group of the highest...
Emillia C. O. Lloyd, Bradley Dempsey, Lindsey Romero
Complex regional pain syndrome is a rare, chronic disorder that leads to pain that may last for years. The disease typically develops four to six weeks after direct trauma, such as an injury or surgery. Diagnosis is made clinically using standardized diagnostic criteria. The...
Vini Vijayan, Fouzia Naeem, Angela F. Veesenmeyer
Strategies to prevent mother-to-child transmission include maternal and infant antiretroviral therapy and formula-feeding instead of breastfeeding. All infants born to mothers with HIV infection should receive antiretroviral postexposure prophylaxis within six to 12 hours...
Octavia Amaechi, Miranda McCann Human, Kaleigh Featherstone
Acetaminophen and nonsteroidal anti-inflammatory drugs are the first-line treatment options for most patients with mild to moderate acute pain. Severe acute pain may necessitate reserved short-term use of opioids with attention to minimizing risk.
Timothy Mott, Gregory Jones, Kimberly Roman
Costochondritis is a common cause of chest pain. The diagnosis is largely based on history and a physical examination that demonstrates reproduction of pain through palpation of the parasternal region of the chest wall, performance of a crowing rooster maneuver, and/or a...
Ada D. Stewart
Can prioritizing primary care save the U.S. health care system?
Wendy S. Rubinstein, Michael Pacanowski
To share its perspective on the state of the science, the FDA has published a table of pharmacogenetic associations related to genetic variants that can affect drug concentrations, therapeutic responses, or adverse events.
Key clinical questions and their evidence-based answers directly from the journal’s content, written by and for family physicians.
Sabrina Silver, James J. Arnold
A Cochrane review compared the levonorgestrel-releasing intrauterine system with progesterone for the treatment of endometrial hyperplasia.
Joseph R. Yancey, Michelle Szczepanik
Surgical treatment for AC joint dislocation of the shoulder does not appear to be superior to conservative management in adults. Surgical therapy increases the risk of hardware complications, infection, and continued discomfort.
Sean Simmons, Aaron Saguil
SARS-CoV-2 antigen tests have an average sensitivity of 68.9% and an average specificity of 99.6%. Accuracy depends on symptom status, time from symptom onset, and test brand.
Howard Tracer, James Pierre
This PPIP quiz is based on the recommendations of the USPSTF.
Michael Grover
A patient develops erythema and warmth on the arm two weeks after receiving the first dose of the mRNA-1273 vaccine against the SARS-CoV-2 virus.
Samuel Tiglao, Nickolas Hadley, Christopher Hodge
A patient with multiple medical conditions presented with nonpurulent cellulitis and MRSA bacteremia.
Rita M. Lahlou, Timothy P. Daaleman
Social isolation and loneliness are increasingly recognized as complex clinical and public health problems, particularly in older adults, leading to adverse mental and physical health outcomes. The COVID-19 pandemic has led to physical distancing policies, which have...
Natasha Pyzocha
The GeneSight test may assist in drug selection and dosing for individuals having difficulty finding an effective option or who have had intolerable adverse effects after trials of several drugs. However, because only a small population of patients are expected to have...
Aaron Gale, Kirsten Stoesser, Katherine Fortenberry, Dominik Ose, Alyssa Migdalski
Selective serotonin reuptake inhibitors and risperidone are moderately effective at decreasing agitation in all types of dementia. Olanzapine and risperidone reduce dementia-related agitation much longer than placebo. Dextromethorphan/quinidine may be effective at reducing...
Chelsea Harris
More comparative data are needed to justify the use of clascoterone over less expensive, currently available therapies for moderate to severe acne. However, systemic absorption of clascoterone is low, and it may serve as a safe alternative for patients 12 years and older who...
Michael J. Arnold, Andrew Buelt
The U.S. Department of Veterans Affairs and U.S. Department of Defense published guidelines for the primary care management of COPD.
Michael J. Arnold
The American Academy of Family Physicians has published guidelines for treating acute exacerbations of COPD based on a systematic review.
Michael J. Arnold
The American Thoracic Society published guidelines for pharmacologic management of COPD and long-term oxygen therapy for COPD and interstitial lung disease based on systematic reviews.
James J. Stevermer, Lynn Fisher, Kenneth W. Lin, Robyn Liu, Daniel Goodenberger, Kenneth Schellhase, Bill Vaughan, Melanie D. Bird
The American Academy of Family Physicians has published guidelines for treating acute exacerbations of COPD.
Josef Finsterer, Fulvio Alexandre Scorza
Reply: Balraj Sing, Parminder Kaur
Andrea Westby, Cassandra M. Jones, Katie A. Loth
Reply: David A. Klein, Jillian Sylvester, Natasha A. Schvey
Amy G. Cantor, Heidi D. Nelson
Reply: Heather L. Paladine, Himabindu Ekanadham, Daniela C. Diaz
HIV is the virus that causes AIDS. It is possible to have HIV infection for a long time before developing AIDS.
All editors in a position to control content for this activity, AFP journal, are required to disclose any relevant financial relationships. View disclosures.
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