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Am Fam Physician. 2024;109(1):87

What is the first-line treatment for chronic rhinosinusitis?

Consistent evidence from randomized controlled trials shows that intranasal saline irrigation and intranasal corticosteroids improve sinonasal symptoms in patients with chronic rhinosinusitis.

When should a child with cryptorchidism (undescended testicle) be referred to a urologist?

Referral for surgical consultation is recommended by six months of age or at the time of diagnosis in older patients.

Is there a difference in the rate of major adverse cardiovascular events when comparing chlorthalidone with hydrochlorothiazide to treat hypertension?

According to a trial of more than 13,000 patients, both medications are effective, and there is no difference in cardiovascular outcomes when hydrochlorothiazide is compared with chlorthalidone. There is a slightly higher risk of hypokalemia with chlorthalidone.

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