Prostatitis encapsulates a spectrum of clinical syndromes that affects approximately 10% to 15% of individuals assigned male at birth.^1–3 It presents with varying degrees of lower urinary tract symptoms (e.g., obstructive, irritative, storage related), pelvic pain, sexual dysfunction, and systemic features. The National Institutes of Health organizes prostatitis into four categories. Categories I and II constitute 10% of cases and include acute and chronic bacterial prostatitis, respectively. Category III (chronic prostatitis/chronic pelvic pain syndrome [CPPS]) and category IV (asymptomatic inflammatory prostatitis) are noninfectious and comprise the remaining 90% of cases.⁴ Identifying prostatitis as bacterial (categories I and II) or nonbacterial (categories III and IV) is critical for timely treatment and appropriate antibiotic use (Table 1).⁵