These key learning points summarize the consensus- and evidence-based recommendations included in this edition. The sources listed here for each statement recommend that physicians perform or implement these actions directly in a clinical setting.

1. Prescribe long-term proton pump inhibitor (PPI) therapy for patients with confirmed gastroesophageal reflux disease (GERD) and acid-related complications, patients with Barrett esophagus and symptomatic GERD, and patients at high risk of bleeding from long-term nonsteroidal anti-inflammatory drug (NSAID) use if they continue to take NSAIDs.
Evidence rating: SORT B
Source: American Gastroenterological Association, reference 45
Website: https://www.gastrojournal.org/article/S0016-5085(17)30091-4/fulltext

2. If Helicobacter pylori is identified in patients with peptic ulcer disease, offer treatment for H pylori infection.
Evidence rating: SORT B
Source: American College of Gastroenterology, reference 97
Website: https://journals.lww.com/ajg/fulltext/2017/02000/acg_clinical_guideline_treatment_
of_helicobacter.12.aspx

3. After management for H pylori infection is completed, testing for proof of eradication should be obtained at least 4 weeks after treatment completion and after PPI therapy has been withheld 1 to 2 weeks.
Evidence rating: SORT C
Source: American College of Gastroenterology, reference 97/
Website: https://journals.lww.com/ajg/fulltext/2017/02000/acg_clinical_guideline_treatment
_of_helicobacter.12.aspx