These key learning points summarize the consensus- and evidence-based recommendations included in this edition. The sources listed here for each statement recommend that physicians perform or implement these actions directly in a clinical setting.

1. Do not prescribe topical or oral antibiotics as monotherapy for acne, as this might increase microbial resistance.
Evidence rating: SORT B
Sources: American Academy of Dermatology (AAD), Pediatrics, references 5, 15
Websites: https://www.jaad.org/article/S0190-9622(15)02614-6/fulltext,
https://publications.aap.org/pediatrics/article-abstract/131/Supplement_3/S163/31260/Evidence-Based-Recommendations-for-the-Diagnosis

2. For children and adolescents with acne, prescribe benzoyl peroxide as a first-line treatment and the mainstay of the treatment regimen.
Evidence rating: SORT B
Sources: AAD, Pediatrics, references 5, 15
Websites: https://www.jaad.org/article/S0190-9622(15)02614-6/fulltext,
https://publications.aap.org/pediatrics/article-abstract/131/Supplement_3/S163/31260/Evidence-Based-Recommendations-for-the-Diagnosis