These key learning points summarize the consensus- and evidence-based recommendations included in this edition. The sources listed here for each statement recommend that physicians perform or implement these actions directly in a clinical setting.

1. For diagnosis of patients with suspected knee osteoarthritis, obtain radiographs including standing anteroposterior, lateral, 45° posteroanterior (Rosenberg), and skyline views.
Strength of Evidence: A
Source: Hsu H, Siwiec R. Knee Arthroplasty. StatPearls Publishing, 2023. Updated July 24, 2023. Accessed October 8, 2024.
Website: https://www.ncbi.nlm.nih.gov/books/NBK507914/

2. For patients who have undergone total knee arthroplasty, initiate a rapid recovery protocol early after surgery.
Strength of recommendation: B
Source: Sattler L, Hing W, Vertullo C. Changes to rehabilitation after total knee replacement. Aust J Gen Pract. 2020;49(9):587-591.
Website: https://www1.racgp.org.au/ajgp/2020/september/changes-to-rehabilitation-after-total- knee-replace

3. In patients with suspected septic arthritis, start empiric antibiotic therapy after joint aspiration is completed. Choose antibiotics based on the pathogens likely to be involved (eg, Staphylococcus aureus, Streptococcus species, gram-negative bacteria) and local resistance patterns.
Strength of recommendation: B
Source: Mathews CJ, Weston VC, Jones A, et al. Bacterial septic arthritis in adults. Lancet. 2010:375(9717):846-855.
Website: https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(09)61595-6/abstract