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Articles

Practical Selection of Antiemetics in the Ambulatory Setting

ZACHARY A. FLAKE, BECKY S. LINN, JAIME R. HORNECKER

Clinicians can improve the effectiveness and cost-effectiveness of antiemetics by targeting the appropriate neurotransmitter pathway that mediates nausea and vomiting. Antihistamines and anticholinergics are most effective in patients with vestibular-mediated nausea secondary...

Diagnosis and Management of Sodium Disorders: Hyponatremia and Hypernatremia

MICHAEL M. BRAUN, CRAIG H. BARSTOW, NATASHA J. PYZOCHA

Plasma osmolality plays a critical role in the treatment of sodium disorders. Hyponatremia and hypernatremia are classified based on volume status. Sodium disorders are diagnosed by findings from the history, physical examination, laboratory studies, and evaluation of volume...

Evaluation and Treatment of Infertility

TAMMY J. LINDSAY, KIRSTEN R. VITRIKAS

Evaluation of infertility should be offered to couples who have not conceived after 12 months of regular, unprotected vaginal intercourse. In addition to a history and physical examination, men should undergo a semen analysis, and women should be assessed for ovulation...

AAFP News Now: AFP Edition

AAFP News: AFP Edition

CMS to Revise Meaningful Use in 2015 | HHS Lays Out Path to Move Away From Fee-for-Service Medicare Payment | Studies Point to Recent Slowdown in Opioid Abuse, but Work Remains | AAFP Warns That EHR Certification Methods Fail Physicians, Patients

Cochrane for Clinicians

Controlled-Release Oxycodone for Neuropathic Pain and Fibromyalgia in Adults

MEGHAN F. RALEIGH, ANGELA M. DUNN

Oxycodone CR has limited effectiveness for the treatment of diabetic neuropathy or postherpetic neuralgia. Evidence is lacking regarding treatment benefit for other neuropathic pain syndromes or fibromyalgia. Adverse effects of oxycodone CR therapy are common.

Risk of Venous Thromboembolism with Use of Combined Oral Contraceptives

AARON SAGUIL

All combined oral contraceptives increase VTE risk. The risk is greater for those containing desogestrel, drospirenone, gestodene (not available in the United States), and cyproterone acetate (not available in the United States) when compared with levonorgestrel. All combined...

Editorials

Improving Quality by Doing Less: Overtreatment

JESSICA HERZSTEIN, MARK EBELL

The third in a series of AFP editorials that addresses the related issues of over-screening, overdiagnosis, and overtreatment. Overtreatment is an important harm that commonly follows overscreening and overdiagnosis.

FPIN's Clinical Inquiries

Obesity and Joint Injuries in Children

BRYAN A. SUNDIN, ELIZABETH MORENO, JON O. NEHER, LEILANI ST. ANNA

Lower extremity injuries are 18% more likely in overweight children, 24% more likely in obese children, and 34% more likely in extremely obese children when compared with normal weight peers. The risk of lower extremity fractures is also increased by 17% in overweight...

Photo Quiz

Blisters Over the Buttocks

PURNIMA BANSAL, BODE ADEBAMBO

A 7-year-old girl with a history of pain in her lower abdomen and buttocks developed multiple bullous lesions in the perirectal area involving the gluteal cleft and both buttocks.

STEPS

Vortioxetine (Brintellix) for the Treatment of Depression

MEGAN K. MAGOVERN, KATHARINE C. DEGEORGE

Current evidence does not support the routine use of vortioxetine in the treatment of depression. Family physicians most often encounter patients with mild to moderate depression, and vortioxetine has not been studied in this population. There is no clear benefit of using...

POEMs

Lung Cancer Screening Is Cost-Effective, but Only If Done Correctly

MARK H. EBELL

The U.S. Preventive Services Task Force (USPSTF) gave lung cancer screening a B recommendation on the basis of the reductions in disease-specific mortality and all-cause mortality seen in the National Lung Screening Trial (NLST). The NLST does not consider cost or cost...

Practice Guidelines

AHA/ASA Release Guideline on Stroke Prevention in Women

AMBER RANDEL

The American Heart Association and American Stroke Association (AHA/ASA) have released a guideline to help physicians identify women with increased risk of stroke and initiate appropriate preventive measures. The guideline includes recommendations on pregnancy and stroke;...

U.S. Preventive Services Task Force Letters to the Editor Information from Your Family Doctor

Infertility: What Women Should Know

Infertility is defined as not being able to get pregnant after 12 months of trying. It may be caused by medical problems in you or your partner. In about 40% of cases, there are factors in both partners. About 25% of couples do not have a clear reason for their infertility....



Disclosure

All editors in a position to control content for this activity, AFP journal, are required to disclose any relevant financial relationships. View disclosures.


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