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Cochrane for Clinicians

Putting Evidence into Practice

Exercise-Based Cardiac Rehabilitation for Adults With Heart Failure

CLINICAL QUESTION

Does exercise-based cardiac rehabilitation improve mortality rates, hospital admission rates, and health-related quality of life in adults who have heart failure (HF) with reduced or preserved ejection fraction?

EVIDENCE-BASED ANSWER

Exercise-based cardiac rehabilitation likely reduces the risk of all-cause hospital admission in adults who have HF with reduced or preserved ejection fraction.1 (Strength of Recommendation [SOR]: A, consistent, good-quality patient-oriented evidence.) Exercise-based cardiac rehabilitation likely improves short-term health-related quality of life in adults with HF with reduced or preserved ejection fraction. (SOR: A, consistent, good-quality patient-oriented evidence.) Exercise-based cardiac rehabilitation does not decrease short-term (up to 12 months) all-cause mortality compared with usual care in adults who have HF with reduced or preserved ejection fraction. (SOR: B, inconsistent or limited-quality patient-oriented evidence.)

PRACTICE POINTERS

HF is a common condition affecting more than 60 million people worldwide.1,2 HF is a clinical syndrome with signs and/or symptoms caused by structural and/or functional cardiac abnormalities.3 In this Cochrane review, patients who had HF with preserved ejection fraction (HFpEF) were defined as having an ejection fraction of 45% or greater, and patients with HF with reduced ejection fraction (HFrEF) were defined as having an ejection fraction of less than 45%.1 Patients with HF often experience a significant reduction in exercise capacity, which can negatively affect quality of life. Exercise-based cardiac rehabilitation is an underused treatment for cardiovascular disease to improve HF symptoms and related outcomes.4 Exercise-based cardiac rehabilitation always includes formal exercise training but may also include education on lifestyle and risk factor modification, counseling, and psychosocial support.1,4 It typically is conducted in person but also may be implemented through home-based models or technology-based models, which may increase access to this intervention.4

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These are summaries of reviews from the Cochrane Library.

This series is coordinated by Corey D. Fogleman, MD, assistant medical editor.

A collection of Cochrane for Clinicians published in AFP is available at https://www.aafp.org/afp/cochrane.

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