Michelle Nelson, Shaunak R. Mulani, Aaron Saguil
Jaundice presents when impairment in bilirubin metabolism occurs. It is typically apparent when serum bilirubin levels are elevated and can indicate serious underlying disease of the liver or biliary tract; jaundice may occur because of intra- or extrahepatic pathology.
Carl Bryce, Theron Liddell, Geoffrey Gideon
Challenges in early childhood can involve a range of normal to problematic behaviors. These behaviors, including sleep issues, thumb sucking, picky eating, school readiness, and oral heath, can affect quality of life if not addressed appropriately.
Ariel Hoffman, Katelyn A. Dolezal, Rob Powell
Numerous infectious and inflammatory conditions affecting the genitourinary tract and adjacent structures can cause dysuria in adults. A comprehensive history, careful physical examination, and appropriate testing are key to correct diagnosis and treatment.
Faith M. Butler, Deborah Rivera Hernandez
Cardinal features of acute bacterial rhinosinusitis are unilateral facial pain or pressure, fever greater than 102°F, and purulent nasal discharge with obstruction of the nasal passages; antibiotics should be reserved for patients without improvement in symptoms after several...
J. Alexander Fraser, Maksim Son, Anastasiya Vinokurtseva
Common high-risk conditions that cause sudden vision loss include acute angle-closure glaucoma, retinal detachment, retinal artery occlusion, giant cell arteritis, and optic neuritis.
Brian Antono, Andrea Dotson
Gastroesophageal reflux symptoms are common, occurring daily in approximately 40% of infants. Gastroesophageal reflux can progress to gastroesophageal reflux disease (GERD) and may lead to complications, such as esophagitis or esophageal stricture. This article reviews the...
Sumi M. Sexton, Matthew Neff
American Family Physician (AFP) kicks off its 75th anniversary year.
Sarina Schrager, Dean A. Seehusen, Sumi M. Sexton, Caroline Richardson, Jon Neher, Nicholas Pimlott, Marjorie Bowman, José Rodríguez, Christopher P. Morley, Li Li, James Dom Dera
This is a joint editorial written by multiple family medicine journal editors about the use of artificial intelligence in family medicine publications.
Kenneth W. Lin
Using shared decision-making for PSA testing for prostate cancer screening is a flawed approach.
Doug Campos-Outcalt
In June 2024, the FDA approved PCV21 (Capvaxive) for adults 18 years and older to prevent invasive pneumococcal disease.
Key clinical questions and their evidence-based answers directly from the journal’s content, written by and for family physicians.
Nicholas Salter, Alexei O. DeCastro
The GOLD report recommends considering inhaled corticosteroid therapy added to a LABA in patients with moderate to severe COPD. Triple therapy is considered, but the GOLD report noted limited available information.
Kevin R. Herrick, Vladimir Shalkevich
Physicians may encounter situations that challenge the boundaries between themselves and their patients. These challenges can lead to instances or allegations of patient exploitation that can result in serious legal and professional consequences for the physician.
Alyssa Bruehlman, Elizabeth Salisbury-Afshar
Psychosocial interventions may increase the rate of sustained alcohol cessation during pregnancy. However, they may have little to no effect on the number of drinks consumed per day or treatment retention.
Arindam Sarkar, Briana Jarrett, Rashmi Rode
Use of ACE inhibitor or ARB therapy reduces progression to end-stage kidney disease in patients with diabetic kidney disease. Neither ACE inhibitor nor ARB therapy has been associated with reduced all-cause or cardiovascular mortality compared with placebo in patients with...
Danish Abdul Alla, Louis Gerges, Judith Philip, Carrie Wirth
Use of antioxidant vitamin or zinc supplements may delay progression of age-related macular degeneration (ARMD) compared with placebo. The addition of docosahexaenoic acid, lutein, zeaxanthin, resveratrol, and hydroxytyrosol to the supplements used in the original Age-Related...
Timothy Mott, Carrie Gray
Nonoperative treatment with antibiotics for uncomplicated acute appendicitis in children is an option but leads to higher numbers of hospital readmissions and subsequent surgeries. The nonoperative approach has a treatment failure rate of approximately 20%, with most...
Courtney Humphrey, Minuette Laessig
A 71-year-old woman presented with a skin lesion on her right cheek.
Angela Puthenveetil, Sameer Suhale
A 3-month-old boy presented with a circular rash.
Iris R. Mabry-Hernandez, Elizabeth Lees
This PPIP quiz is based on the recommendations of the USPSTF.
The USPSTF recommends screening for hypertensive disorders in pregnant persons with blood pressure measurements throughout pregnancy.
Stephen R. Foster, Kodi M. Liddell
Gepirone produces minimal reductions in symptoms compared with placebo. Adverse effects are common, and baseline testing is required before starting treatment with gepirone. Given these issues and the high cost of the medication, its use should be limited.
Michael J. Arnold
The American Academy of Orthopaedic Surgeons has published guidelines for management of hip osteoarthritis.
Patrick Bagley, David Smith
The Society of Critical Care Medicine developed guidelines to optimize rapid sequence intubation.
Kento Sonoda
Reply: Elisabeth Poorman, Brianna M. McQuade, Sarah Messmer
Jeff Unger
Reply: Sandy Robertson, Emily E. Peacock, Robert Scott
All editors in a position to control content for this activity, AFP journal, are required to disclose any relevant financial relationships. View disclosures.
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